Biography
Biography: Bimal Roy Krishna
Abstract
Pain Management an integral part of therapeutics and clinical medicine has evolved immensely over the years to provide adequate support and control of pain.
Significant adverse physiological and psychological effects manifest due to inadequate pain control. The physiology and pathology of pain whether peripheral or central involves nociception and transmission from the injured tissue-skin, muscle or viscera. Pain associated with trauma and terminal diseases requires aggressive control beyond the inhibition of the inflammatory mediators such as the prostaglandins.
Non-Steroidal Anti-inflammatory drugs have been the mainstay of treatment. However, failure of NSAID’s to treat pain or more chronic conditions require a Step one Up approach which would then introduce the opioids which address central mechanisms and are also used to treat severe pain particularly those associated with terminal illness and myocardial infarcts. The mechanisms of action, of opioids are similar however they differ in pharmacokinetic parameters.
This presentation addresses the current approach to pain management.