Biography
Biography: Ganapathy Sivakumar
Abstract
Plant-based drugs to treat human lethal diseases have been elicited with cutting-edge clinical research. Colchicine is an important alkaloid-based drug used to treat gout, cardiovascular disease, etc. However, plant-based biopharmaceuticals and industrial-scale development pose several challenges in biomanufacturing. Biorhizome is a new technology to enhance the colchicine biomanufacturing. Nevertheless, the biochemical pathways and regulatory networks in the biorhizomes that control colchicine biosynthesis are yet to be characterized, leaving a significant barrier to improving colchicine biomanufacturing. The presentation will emphasize the biomanufacturing of biopharmaceuticals and improving the commercial-scale biorhizome-based colchicine.