Madhu Anand
Dr. B.R. Ambedkar University, India
Title: Environmental exposure to persistent organochlorine pesticides and risk of breast cancer in indian females
Biography
Biography: Madhu Anand
Abstract
In India, breast cancer is the most common type of cancer among women, although the incidences are very low i.e., 19 per 100,000 compared to the United States and United Kingdom, where the incidence rates are quite higher i.e., 101 in United States and 87 in the UK. But the death per incidence ratio is highest in India is about 50%, followed by 30% in China and 18% in the United States. The etiology is remains, unknown but environmental, genetic, nutritional and hormonal factors are established as contributory risk factors. The majority of breast cancers have been proposed to be of environmental origin. Among the environmental factors organochlorine pesticide have has been suggested to play a causative role in the etiology of breast cancer. Organochlorine pesticides are widely dispersed and persist in the environment, act as xenoestrogen, get stored in adipose tissues and act as tumor promoter. Keeping all the views in mind, we have planned a multicentric study to evaluate the risk of breast cancer in different regions of India. Knowledge and awareness of breast cancer due to pollution is yet to accomplish desired goals and impact, therefore urgent intervention by the relevant bodies to educate and enlightening of the females is required.
